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The Clonal Evolution of Tumor Cell Populations

Peter C. Nowell̀ · Science · 1976 · 6.5K citations

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Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC

Patrice J. Morin, Andrew B. Sparks, Vladimír Kořínek et al. · Science · 1997 · 3.9K citations

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Requirement for p53 and p21 to Sustain G ₂ Arrest After DNA Damage

Fred Bunz, Annie Dutriaux, Christoph Lengauer et al. · Science · 1998 · 2.8K citations

Life Sciences, Cell Biology, Molecular Biology +17

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

Yurij Ionov, Miguel A. Peinado, Sergei Malkhosyan et al. · Nature · 1993 · 2.7K citations

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Genetic instability in colorectal cancers

Christoph Lengauer, Kenneth W. Kinzler, Bert Vogelstein · Nature · 1997 · 2K citations

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