Concepedia

Genetic Instability

Genetic Instability is a biological phenomenon characterized by an increased tendency for alterations in the genome, particularly in the form of spontaneous mutations, during cell division, thereby deviating from the stable genetic transmission typically observed in vegetatively propagated plants such as grapevines.

1.2K

Publications

88.5K

Citations

6.1K

Authors

1.6K

Institutions

Publications per year

2017–2026

138

Parents

Publications

1.2K

The Clonal Evolution of Tumor Cell Populations

Peter C. Nowell̀ · Science · 1976 · 6.5K citations

, , +17

Variation of the CGG repeat at the fragile X site results in genetic instability: Resolution of the Sherman paradox

Ying‐Hui Fu, Derek P.A. Kuhl, Antonio Pizzuti et al. · Cell · 1991 · 2.1K citations

, , +8

Genetic instability in colorectal cancers

Christoph Lengauer, Kenneth W. Kinzler, Bert Vogelstein · Nature · 1997 · 2K citations

, , +14

CHROMOSOME ORGANIZATION AND GENIC EXPRESSION

Barbara McClintock · Cold Spring Harbor Symposia on Quantitative Biology · 1951 · 1.2K citations

, , +12

Repeat instability: mechanisms of dynamic mutations

Christopher E. Pearson, Kerrie Nichol Edamura, John D. Cleary · Nature Reviews Genetics · 2005 · 914 citations

, , +12

1–5 of 1.2K

Authors

6.1K

  1. BD
    Bernard Decaris

    Laboratoire de Chimie Physique et Microbiologie pour l'Environnement, France

    13 publications · 372 citations

    12

    h-index

  2. BV
    Bert Vogelstein

    Johns Hopkins University, United States

    12 publications · 5.2K citations

    12

    h-index

  3. CL
    Christoph Lengauer

    Johns Hopkins University, United States

    11 publications · 4.5K citations

    11

    h-index

  4. CC
    Christophe Cazaux

    Centre National de la Recherche Scientifique, France

    12 publications · 775 citations

    11

    h-index

  5. KM
    Karen M. Vásquez

    The University of Texas MD Anderson Cancer Center, United States

    10 publications · 1.1K citations

    10

    h-index

1–5 of 6.1K

Institutions

1.6K

  1. Centre National de la Recherche Scientifique

    Paris, France

    31 h-index

    218 publications

    13.9K citations

  2. Johns Hopkins University

    Baltimore, United States

    28 h-index

    108 publications

    23.1K citations

  3. National Institutes of Health

    Bethesda, United States

    24 h-index

    95 publications

    12.1K citations

  4. The University of Texas MD Anderson Cancer Center

    Houston, United States

    22 h-index

    104 publications

    10.4K citations

  5. Inserm

    Paris, France

    21 h-index

    115 publications

    8.1K citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    21 h-index

    73 publications

    46K citations

  7. Harvard University

    Cambridge, United States

    20 h-index

    60 publications

    5.7K citations

  8. Johns Hopkins Medicine

    Baltimore, United States

    19 h-index

    54 publications

    10.1K citations

1–8 of 1.6K

Venues

  1. PubMed

    Repository · 123 publications · 9.4K citations

    54

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 53 publications · 7.4K citations

    39

    h-index

  3. Cancer Research

    30 publications · 3.6K citations

    28

    h-index

  4. Nucleic Acids Research

    33 publications · 2.5K citations

    25

    h-index

  5. Molecular and Cellular Biology

    MCB · 23 publications · 2.6K citations

    22

    h-index

1–5