CYP1A2 phenotype and genotype in a population from the Carboniferous Region of Coahuila, Mexico

Functional significance of a C→A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine

Christoph Sachse, Jürgen Brockmöller, Steffen Bauer et al. · British Journal of Clinical Pharmacology · 1999 · 750 citations · Full text

Life Sciences, Genetics, Pharmacology +14

Reactions and significance of cytochrome P-450 enzymes

F. Peter Guengerich · Journal of Biological Chemistry · 1991 · 603 citations · Full text

Life Sciences, Biochemistry, Enzyme Mechanism +16

Determination of hydroxylated metabolites of polycyclic aromatic hydrocarbons in urine

F.J. Jongeneelen, R. B. M. Anzion, P.Th. Henderson · Journal of Chromatography B Biomedical Sciences and Applications · 1987 · 424 citations

Life Sciences, Biochemistry, Toxicology +11

Genetic Polymorphism in the 5'-Flanking Region of HumanCYP1A2 Gene: Effect on the CYP1A2 Inducibility in Humans

Mitsutoshi Nakajima, Tsuyoshi Yokoi, Mayumi Mizutani et al. · The Journal of Biochemistry · 1999 · 347 citations

Medicine, Molecular Genetics, Pharmacology +12

Variability in caffeine metabolism

Denis M. Grant, Bing Tang, W. Kalow · Clinical Pharmacology & Therapeutics · 1983 · 258 citations

Medicine, Pharmacokinetics, Pharmacology +17