Concepedia

The anti-diabetic drug metformin inhibits vascular endothelial growth factor expression via the mammalian target of rapamycin complex 1/hypoxia-inducible factor-1α signaling pathway in ELT-3 cells

Mari Tadakawa, Takashi Takeda, Bin Li, Kenji Tsuiji, Nobuo Yaegashi

Molecular and Cellular Endocrinology · 2014 · 46 citations · 34 references

DOI

Concepts

References

34

Activation of Vascular Endothelial Growth Factor Gene Transcription by Hypoxia-Inducible Factor 1

Jo A. Forsythe, Bing‐Hua Jiang, Narayan V. Iyer et al. · Molecular and Cellular Biology · 1996 · 3.9K citations · Full text

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

Dana M. Gwinn, David B. Shackelford, Daniel F. Egan et al. · Molecular Cell · 2008 · 3.7K citations · Full text

, , +5

mTOR Inhibition Induces Upstream Receptor Tyrosine Kinase Signaling and Activates Akt

Kathryn O’Reilly, F. Rojo, Qing‐Bai She et al. · Cancer Research · 2006 · 2.5K citations · Full text

Raptor, a Binding Partner of Target of Rapamycin (TOR), Mediates TOR Action

Kenta Hara, Yoshiko Maruki, K. Yoshino et al. · Cell · 2002 · 1.8K citations · Full text

, , +6

PI3K/AKT/mTOR Pathway in Angiogenesis

Jayashree Karar, Amit Maity · Frontiers in Molecular Neuroscience · 2011 · 1.4K citations · Full text