Concepedia

Both Decreased and Increased SRPK1 Levels Promote Cancer by Interfering with PHLPP-Mediated Dephosphorylation of Akt

Pingping Wang, Zhihong Zhou, Anchang Hu, Claudio P. Albuquerque, Yu Zhou, Lixin Hong, Emma Sierecki, Masahiko Ajiro, Michael J. Kruhlak, Curtis C. Harris,

Molecular Cell · 2014 · 155 citations · 39 references

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39

Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a

Manuel Serrano, Athena W. Lin, Mila E. McCurrach et al. · Cell · 1997 · 5.1K citations · Full text

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TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth

Ken Inoki, Hongjiao Ouyang, Tianqing Zhu et al. · Cell · 2006 · 1.4K citations

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An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior

Jean‐Martin Beaulieu, Tatyana D. Sotnikova, Sébastien Marion et al. · Cell · 2005 · 966 citations · Full text

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PHLPP: A Phosphatase that Directly Dephosphorylates Akt, Promotes Apoptosis, and Suppresses Tumor Growth

Tianyan Gao, Frank B. Furnari, Alexandra C. Newton · Molecular Cell · 2005 · 911 citations · Full text

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The PTEN–PI3K pathway: of feedbacks and cross-talks

Arkaitz Carracedo, Pier Paolo Pandolfi · Oncogene · 2008 · 893 citations

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