Concepedia
Toxicology Letters · 2011 · 38 citations · 46 references
Signal TransductionProtein ExpressionGene RegulationPxr Transcription FactorSystems BiologyMedicineCell BiologyGene ExpressionTranscription Regulation
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Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
Jo Vandesompele, Katleen De Preter, Filip Pattyn et al. · Genome biology · 2002 · 19.7K citations · Full text
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver
Jay D. Horton, Joseph L. Goldstein, Michael S. Brown · Journal of Clinical Investigation · 2002 · 3.9K citations · Full text
Neutral red uptake assay for the estimation of cell viability/cytotoxicity
Guillermo Repetto, Ana del Peso, Jorge L. Zurita · Nature Protocols · 2008 · 2.1K citations
Health Sciences, Medicine, Bioanalysis +11
The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.
J�rgen Lehmann, David D. McKee, M. A. Watson et al. · Journal of Clinical Investigation · 1998 · 1.6K citations · Full text
Genetics, Cyp3a4 Gene, Mouse Pxr Reveals +18
The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity
Jeff L. Staudinger, Bryan Goodwin, Stacey A. Jones et al. · Proceedings of the National Academy of Sciences · 2001 · 1.3K citations · Full text