Concepedia

Aflatoxins upregulate CYP3A4 mRNA expression in a process that involves the PXR transcription factor

Marcin Ratajewski, Aurelia Walczak‐Drzewiecka, Anna Sałkowska, Jarosław Dastych

Toxicology Letters · 2011 · 38 citations · 46 references

DOI

Concepts

References

46

Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes

Jo Vandesompele, Katleen De Preter, Filip Pattyn et al. · Genome biology · 2002 · 20.1K citations · Full text

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SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver

Jay D. Horton, Joseph L. Goldstein, Michael S. Brown · Journal of Clinical Investigation · 2002 · 4K citations · Full text

, , +17

Neutral red uptake assay for the estimation of cell viability/cytotoxicity

Guillermo Repetto, Ana del Peso, Jorge L. Zurita · Nature Protocols · 2008 · 2.2K citations

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The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.

J�rgen Lehmann, David D. McKee, M. A. Watson et al. · Journal of Clinical Investigation · 1998 · 1.6K citations · Full text

, , +14

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

Jeff L. Staudinger, Bryan Goodwin, Stacey A. Jones et al. · Proceedings of the National Academy of Sciences · 2001 · 1.4K citations · Full text

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