Regulation of protein kinase C by short term hyperglycaemia in human platelets in vivo and in vitro

The Effect of Intensive Treatment of Diabetes on the Development and Progression of Long-Term Complications in Insulin-Dependent Diabetes Mellitus

New England Journal of Medicine · 1993 · 24.7K citations · Full text

Medicine, Endocrinology, Internal Medicine +14

Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)

The Lancet · 1998 · 20.1K citations

Medicine, Endocrinology, Pharmacotherapy +13

Impaired glucose tolerance is a risk factor for cardiovascular disease, but not impaired fasting glucose. The Funagata Diabetes Study.

Masato Tominaga, Hideyuki Eguchi, Hideo Manaka et al. · Diabetes Care · 1999 · 1.2K citations

Medicine, Endocrinology, Internal Medicine +13

Preferential elevation of protein kinase C isoform beta II and diacylglycerol levels in the aorta and heart of diabetic rats: differential reversibility to glycemic control by islet cell transplantation.

Toyoshi Inoguchi, Ruggero Battan, Eugene S. Handler et al. · Proceedings of the National Academy of Sciences · 1992 · 740 citations

Life Sciences, Biochemistry, Endocrinology +14

Free radical generation by early glycation products: A mechanism for accelerated atherogenesis in diabetes

Cathleen J. Mullarkey, Diane Edelstein, Michael Brownlee · Biochemical and Biophysical Research Communications · 1990 · 693 citations

Life Sciences, Biochemistry, Endocrinology +13