Michael Brownlee

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

Takeshi Nishikawa, Diane Edelstein, Xue Du et al. · Nature · 2000 · 4.2K citations

Metabolic Syndrome, Biochemistry, Mitochondrial Function +11

Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia

Assam El‐Osta, Daniella Brasacchio, Dachun Yao et al. · The Journal of Experimental Medicine · 2008 · 1.1K citations · Full text

Free radical generation by early glycation products: A mechanism for accelerated atherogenesis in diabetes

Cathleen J. Mullarkey, Diane Edelstein, Michael Brownlee · Biochemical and Biophysical Research Communications · 1990 · 692 citations

Metabolic Syndrome, Early Glycation Products, Glycosylation +12

Pericytes and the Pathogenesis of Diabetic Retinopathy

Hans-Peter Hammes, Jihong Lin, Oliver Renner et al. · Diabetes · 2002 · 659 citations · Full text

Leptin Induces Mitochondrial Superoxide Production and Monocyte Chemoattractant Protein-1 Expression in Aortic Endothelial Cells by Increasing Fatty Acid Oxidation via Protein Kinase A

Sho‐ichi Yamagishi, Diane Edelstein, Xue-Liang Du et al. · Journal of Biological Chemistry · 2001 · 620 citations · Full text

Lipid Peroxidation, Immunology, Manganese Superoxide Dismutase +22