Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy

Hans-Peter Hammes, Xueliang Du, Diane Edelstein, +11

Nature Medicine

Metabolic SyndromeDiabetic RetinopathyOcular DiseaseOphthalmologyMajor Pathways +10

Pericytes and the Pathogenesis of Diabetic Retinopathy

Hans-Peter Hammes, Jihong Lin, Oliver Renner, +5

Diabetes

Angiopoietin-2 Causes Pericyte Dropout in the Normal Retina

Hans-Peter Hammes, Jihong Lin, Patrick Wagner, +7

Diabetes

InflammationNormal RetinaDiabetic RetinopathyPericyte LossRetina +11

High Glucose Increases Angiopoietin-2 Transcription in Microvascular Endothelial Cells through Methylglyoxal Modification of mSin3A

Dachun Yao, Tetsuya Taguchi, Takeshi Matsumura, +9

Journal of Biological Chemistry

Hyperglycemia Impairs Proteasome Function by Methylglyoxal

Markus A. Queisser, Dachun Yao, Sven Geisler, +5

Diabetes

Potential Role for ADAM15 in Pathological Neovascularization in Mice

Keisuke Horiuchi, Gisela Weskamp, Lawrence Lum, +9

Molecular and Cellular Biology

AngiogenesisDevelopmental BiologyTissue DevelopmentPathological NeovascularizationBone Morphogenic Protein +11

Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy

Jiong Hu, Sarah Dziumbla, Jihong Lin, +19

Nature

Diabetic RetinopathyOcular DiseaseOphthalmologyMedicineDiabetes +2

EphB4 controls blood vascular morphogenesis during postnatal angiogenesis

Ralf Erber, Uta Eichelsbacher, Violetta Powajbo, +7

The EMBO Journal

Developmental BiologyAngiogenesisVascular BiologyNeovascularizationBlood Vascular Morphogenesis +2

Synaptojanin-2 Binding Protein Stabilizes the Notch Ligands DLL1 and DLL4 and Inhibits Sprouting Angiogenesis

Mohamed Adam, Caroline Berger, Anja Feldner, +8

Circulation Research

Inhibition of Rho-dependent kinases ROCK I/II activates VEGF-driven retinal neovascularization and sprouting angiogenesis

Daniel Epting, Katrin Kern, Christian Dietz, +4

American Journal of Physiology-Heart and Circulatory Physiology

Vegf-driven Retinal NeovascularizationAngiogenesisSmall Gtpase RhoaRetinaReceptor Tyrosine Kinase +14