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An analysis of replicative senescence in dermal fibroblasts derived from chronic leg wounds predicts that telomerase therapy would fail to reverse their disease-specific cellular and proteolytic phenotype

Tissue EngineeringReplicative SenescenceFibrosisTelomerase TherapyChronic LegCellular SenescenceWound HealingDermatologyMedicineCell BiologyExtracellular Matrix