Fiona S. Wyllie

High frequency of ras oncogene activation in all stages of human thyroid tumorigenesis.

N R Lemoine, E S Mayall, Fiona S. Wyllie et al. · PubMed · 1989 · 420 citations

Medicine, Molecular Biology, Oncology +16

Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts

Fiona S. Wyllie, Christopher J. Jones, Julia W. Skinner et al. · Nature Genetics · 2000 · 329 citations

Life Sciences, Cell Biology, Molecular Biology +14

Evidence that transcriptional activation by p53 plays a direct role in the induction of cellular senescence.

Jane Bond, Michele F. Haughton, Jeremy P. Blaydes et al. · PubMed · 1996 · 148 citations

Life Sciences, Cell Biology, Molecular Biology +12

Control of Replicative Life Span in Human Cells: Barriers to Clonal Expansion Intermediate Between M1 Senescence and M2 Crisis

Jane Bond, Michele F. Haughton, J M Rowson et al. · Molecular and Cellular Biology · 1999 · 103 citations

Medicine, Cell Biology, Oncology +17

Evidence for a Telomere-Independent “Clock” Limiting <i>RAS</i> Oncogene-Driven Proliferation of Human Thyroid Epithelial Cells

Christopher J. Jones, David Kipling, Mark R. Morris et al. · Molecular and Cellular Biology · 2000 · 88 citations · Full text

Medicine, Genetics, Oncology +17