Concepedia

Role of the amino-terminal domains of MEKKs in the activation of NFκB and MAPK pathways and in the regulation of cell proliferation and apoptosis

Christelle Bonvin, Audrey Guillon, Miguel X. van Bemmelen, Pär Gerwins, Gary L. Johnson, Christian Widmann

Cellular Signalling · 2002 · 65 citations · 26 references

DOI

Concepts

References

26

Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis

Zhengui Xia, Martin Dickens, Joël Raingeaud et al. · Science · 1995 · 5.3K citations

, , +16

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain.

Masahiko Hibi, Anning Lin, Tod Smeal et al. · Genes & Development · 1993 · 1.9K citations · Full text

, , +15

A Family of Stress-Inducible GADD45-like Proteins Mediate Activation of the Stress-Responsive MTK1/MEKK4 MAPKKK

Mutsuhiro Takekawa, Haruo Saito · Cell · 1998 · 753 citations · Full text

, , +14

Activation of the IκBα Kinase Complex by MEKK1, a Kinase of the JNK Pathway

Frank S. Lee, Jeremiah Hagler, Zhijian J. Chen et al. · Cell · 1997 · 713 citations · Full text

, , +13

The Regulation of Anoikis: MEKK-1 Activation Requires Cleavage by Caspases

Michael H. Cardone, Guy S. Salvesen, Christian Widmann et al. · Cell · 1997 · 507 citations · Full text

, , +9