Association of Systemic Lupus Erythematosus with <i>C8orf13–BLK</i> and <i>ITGAM–ITGAX</i>

Abstract

We identified and then confirmed through replication two new genetic loci for SLE: a promoter-region allele associated with reduced expression of BLK and increased expression of C8orf13 and variants in the ITGAM-ITGAX region.