Concepedia

Sequence variations in the UDP-glucuronosyltransferase 2B7 (UGT2B7) gene: identification of 10 novel single nucleotide polymorphisms (SNPs) and analysis of their relevance to morphine glucuronidation in cancer patients

M. S. T. van Holthe, T N Rakvåg, Pål Klepstad, Jeffrey R. Idle, S. Kaasa, Hans E. Krokan, Frank Skorpen

The Pharmacogenomics Journal · 2003 · 163 citations · 26 references

DOI

Concepts

References

26

The LightCycler <sup>TM</sup> : A Microvolume Multisample Fluorimeter with Rapid Temperature Control

Carl T. Wittwer, Kirk M. Ririe, Richard Andrew et al. · BioTechniques · 1997 · 899 citations · Full text

, , +22

Determinants of Substitution Rates in Mammalian Genes: Expression Pattern Affects Selection Intensity but Not Mutation Rate

Laurent Duret, Dominique Mouchiroud · Molecular Biology and Evolution · 2000 · 531 citations · Full text

Human UGT2B7 catalyzes morphine glucuronidation.

Birgit L. Coffman, Gladys R. Rios, Christopher D. King et al. · PubMed · 1997 · 426 citations

, , +13

The glucuronidation of opioids, other xenobiotics, and androgens by human UGT2B7Y(268) and UGT2B7H(268).

Birgit L. Coffman, Christopher D. King, Gladys R. Rios et al. · PubMed · 1998 · 326 citations

, , +17

Increased Immune Response Elicited by DNA Vaccination with a Synthetic gp120 Sequence with Optimized Codon Usage

Stefanie André, Brian Seed, Josef Eberle et al. · Journal of Virology · 1998 · 305 citations · Full text