Uncoupling protein 2 deficiency aggravates astrocytic endoplasmic reticulum stress and nod-like receptor protein 3 inflammasome activation

Impairment of the Ubiquitin-Proteasome System by Protein Aggregation

Neil Bence, Roopal M. Sampat, Ron R. Kopito · Science · 2001 · 2.2K citations

Life Sciences, Biochemistry, Molecular Biology +17

Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production

Denis Arsenijevic, Hiroki Onuma, Claire Pecqueur et al. · Nature Genetics · 2000 · 1.1K citations

Life Sciences, Genetics, Immunology +16

Uncoupling Protein-2 Negatively Regulates Insulin Secretion and Is a Major Link between Obesity, β Cell Dysfunction, and Type 2 Diabetes

Chenyu Zhang, György Baffy, Pascale Perret et al. · Cell · 2001 · 916 citations · Full text

Medicine, Endocrinology, Physiology +17

Immunolocalization of peroxisome proliferator-activated receptors and retinoid x receptors in the adult rat CNS

Sandra Moreno, Stefano Farioli‐Vecchioli, Maria Paola Cerù · Neuroscience · 2003 · 581 citations

Life Sciences, Neurobiology, Neuroscience +11

Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte

Pei‐Chun Chen, Marcelo R. Vargas, Amar K. Pani et al. · Proceedings of the National Academy of Sciences · 2009 · 579 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17