Overcoming Drug Development Bottlenecks With Repurposing: Old drugs learn new tricks

β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression

Jeffrey D. Rothstein, Sarjubhai A. Patel, Melissa R. Regan et al. · Nature · 2005 · 1.5K citations

Life Sciences, Neuroscience, Pharmacology +14

<i>N</i>-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5- (tetrahydro-2<i>H</i>-pyran-4-yloxy)quinazolin-4-amine, a Novel, Highly Selective, Orally Available, Dual-Specific c-Src/Abl Kinase Inhibitor

Laurent Hennequin, J M Allen, J. Breed et al. · Journal of Medicinal Chemistry · 2006 · 367 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Nonsteroidal Anti-Inflammatory Drugs Can Lower Amyloidogenic Aß ₄₂ by Inhibiting Rho

Yan Zhou, Su Yuan, Baolin Li et al. · Science · 2003 · 310 citations

Life Sciences, Neuroscience, Pharmacology +17

Estrogen — a potential treatment for schizophrenia

Jayashri Kulkarni, Axel Riedel, A.R. de Castella et al. · Schizophrenia Research · 2001 · 225 citations

Medicine, Pharmacotherapy, Psychiatry +12

Synthesis and biological activity of several amino analogues of thymidine.

Tai‐Shun Lin, William H. Prusoff · PubMed · 1978 · 177 citations

Medicine, Medicinal Chemistry, Oncology +14