Concepedia

Structure-based Repurposing

Structure-Based Repurposing is a drug repurposing approach that identifies new therapeutic uses for existing compounds by analyzing their three-dimensional molecular structures to predict interactions with target proteins.

616

Publications

31.3K

Citations

3.6K

Authors

1.2K

Institutions

Publications per year

2017–2026

495

Parents

Children

Publications

616

Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing

Laura Riva, Shuofeng Yuan, Xin Yin et al. · Nature · 2020 · 856 citations · Full text

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Predicting commercially available antiviral drugs that may act on the novel coronavirus (SARS-CoV-2) through a drug-target interaction deep learning model

Bo Ram Beck, Bonggun Shin, Yoonjung Choi et al. · Computational and Structural Biotechnology Journal · 2020 · 790 citations · Full text

, , +16

Fast Identification of Possible Drug Treatment of Coronavirus Disease-19 (COVID-19) through Computational Drug Repurposing Study

Junmei Wang · Journal of Chemical Information and Modeling · 2020 · 495 citations · Full text

, , +17

Activity profiling and crystal structures of inhibitor-bound SARS-CoV-2 papain-like protease: A framework for anti–COVID-19 drug design

Wioletta Rut, Zongyang Lv, Mikołaj Żmudziński et al. · Science Advances · 2020 · 483 citations · Full text

, , +14

Prediction of the SARS-CoV-2 (2019-nCoV) 3C-like protease (3CLpro) structure: virtual screening reveals velpatasvir, ledipasvir, and other drug repurposing candidates

Yu Wai Chen, Chin-Pang Yiu, Kwok‐Yin Wong · F1000Research · 2020 · 449 citations · Full text

, , +17

1–5 of 616

Authors

3.6K

  1. UY
    Usha Y. Nayak

    Manipal Academy of Higher Education, India

    5 publications · 234 citations

    5

    h-index

  2. MP
    Michael P. Pollastri

    Northeastern University, United States

    5 publications · 273 citations

    5

    h-index

  3. DP
    Dragoș Paul Mihai

    Carol Davila University of Medicine and Pharmacy, Romania

    5 publications · 91 citations

    5

    h-index

  4. MJ
    Monika Jain

    Sharda University, India

    4 publications · 426 citations

    4

    h-index

  5. TI
    Tudor I. Oprea

    University of New Mexico, United States

    4 publications · 757 citations

    4

    h-index

1–5 of 3.6K

Institutions

1.2K

  1. King Abdulaziz University

    Jeddah, Saudi Arabia

    12 h-index

    35 publications

    1.4K citations

  2. King Saud University

    Riyadh, Saudi Arabia

    10 h-index

    21 publications

    549 citations

  3. Academy of Scientific and Innovative Research

    Ghaziabad, India

    9 h-index

    30 publications

    2.4K citations

  4. National Research Centre

    Giza, Egypt

    9 h-index

    13 publications

    504 citations

  5. Sharda University

    Greater Noida, India

    8 h-index

    21 publications

    2.8K citations

  6. Manipal Academy of Higher Education

    Manipal, India

    8 h-index

    31 publications

    1.4K citations

  7. University of Delhi

    New Delhi, India

    8 h-index

    16 publications

    611 citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    8 h-index

    24 publications

    1.1K citations

1–8 of 1.2K

Venues

  1. Journal of Biomolecular Structure and Dynamics

    69 publications · 4.3K citations

    31

    h-index

  2. ChemRxiv

    Repository · 30 publications · 888 citations

    17

    h-index

  3. Molecules

    17 publications · 621 citations

    16

    h-index

  4. Scientific Reports

    16 publications · 605 citations

    15

    h-index

  5. European Journal of Medicinal Chemistry

    18 publications · 687 citations

    15

    h-index

1–5