Cationic lipid nanosystems as carriers for nucleic acids

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

Catherine S. Manno, Glenn F. Pierce, Valder R. Arruda et al. · Nature Medicine · 2006 · 2.1K citations

Life Sciences, Hematology, Molecular Genetics +9

A tetrazolium-based colorimetric MTT assay to quantitate human monocyte mediated cytotoxicity against leukemic cells from cell lines and patients with acute myeloid leukemia

Arjan A. van de Loosdrecht, R.H.J. Beelen, GJ Ossenkoppele et al. · Journal of Immunological Methods · 1994 · 802 citations · Full text

Medicine, Hematology, Oncology +7

Immune responses to adenovirus and adeno-associated virus in humans

Narendra Chirmule, Kathleen J. Propert, Susan Magosin et al. · Gene Therapy · 1999 · 681 citations

Life Sciences, Immunology, Infectious Diseases +14

Physicochemical characterization of lipid nanoparticles and evaluation of their drug loading capacity and sustained release potential

Kirsten Westesen, Heike Bunjes, Manuel Koch · Journal of Controlled Release · 1997 · 535 citations

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +17

Body distribution in mice of intravenously injected camptothecin solid lipid nanoparticles and targeting effect on brain

Shi Cheng Yang, Li Fang Lu, Ying Cai et al. · Journal of Controlled Release · 1999 · 470 citations

Pharmacy, Pharmaceutics, Pharmacology +14