Metabolism of [1-14C] — arachidonic acid by cultured calf aortic endothelial cells: Evidence for the presence of a lipoxygenase pathway

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

Jordi Folch, Marjorie B. Lees, G H S Stanley · Journal of Biological Chemistry · 1957 · 64.9K citations · Full text

Life Sciences, Biochemistry, Bioseparations +11

An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

Salvador Moncada, Ryszard J. Gryglewski, S Bunting et al. · Nature · 1976 · 3.6K citations

Medicine, Biochemistry, Pharmacology +16

Transformation of arachidonic acid and homo-gamma-linolenic acid by rabbit polymorphonuclear leukocytes. Monohydroxy acids from novel lipoxygenases

P Borgeat, Mats Hámberg, Bengt Samuelsson · Journal of Biological Chemistry · 1976 · 642 citations · Full text

Life Sciences, Biochemistry, Cellular Metabolism +16

Arachidonate lipoxygenase in blood platelets

D.H. Nugteren · Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism · 1975 · 619 citations

Medicine, Biochemistry, Hematology +14

The role of lipids in platelet function: with particular reference to the arachidonic acid pathway.

Aaron J. Marcus · Journal of Lipid Research · 1978 · 363 citations · Full text

Medicine, Biochemistry, Hematology +16