Lung cancer patients’ CD4+ T cells are activated in vitro by MHC II cell-based vaccines despite the presence of myeloid-derived suppressor cells

Cancer Statistics, 2007

Ahmedin Jemal, Rebecca L. Siegel, Elizabeth Ward et al. · CA A Cancer Journal for Clinicians · 2007 · 7.5K citations · Full text

Medicine, Oncology, Cancer Epidemiology +16

Prospective Randomized Trial of Docetaxel Versus Best Supportive Care in Patients With Non–Small-Cell Lung Cancer Previously Treated With Platinum-Based Chemotherapy

Frances A. Shepherd, Janet Dancey, Rodryg Ramlau et al. · Journal of Clinical Oncology · 2000 · 2.2K citations

Medicine, Oncology, Pharmacology +16

CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes

Edith M. Janssen, Edward E. Lemmens, Tom Wolfe et al. · Nature · 2003 · 1.6K citations

Life Sciences, Cell Biology, Immunology +15

Induction of Tumor Immunity by Removing CD25+CD4+ T Cells: A Common Basis Between Tumor Immunity and Autoimmunity

Jun Shimizu, Sayuri Yamazaki, Shimon Sakaguchi · The Journal of Immunology · 1999 · 1.5K citations · Full text

Life Sciences, Immunology, Oncology +17

Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell Memory

Devon J. Shedlock, Hao Shen · Science · 2003 · 1.4K citations

Life Sciences, Immunology, Infectious Diseases +17