Immunity · 2014 · 241 citations · 59 references
Life SciencesBiomedical SciencesImmunologyCellular ImmunologyImmunoregulationInnate ImmunityCell-mediated ImmunityImmune FunctionImmune PhysiologyImmune RegulationImmune ResponseImmune SystemImmune Activation ThresholdsImmune Cell ActivationImmune Effector FunctionsImmune Function TestingImmune Response AssessmentImmune Response RegulationImmune System Activation ThresholdsImmunological Mechanisms
59
Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in <i>Tlr4</i> Gene
Alexander Poltorak, Xiaolong He, Irina Smirnova et al. · Science · 1998 · 7.6K citations
A Toll-like receptor recognizes bacterial DNA
Hiroaki Hemmi, Osamu Takeuchi, Taro Kawai et al. · Nature · 2000 · 6.4K citations
Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
Lena Alexopoulou, Agnieszka Czopik Holt, Ruslan Medzhitov et al. · Nature · 2001 · 6.1K citations
Gout-associated uric acid crystals activate the NALP3 inflammasome
Fabio Martinon, Virginie Pétrilli, Annick Mayor et al. · Nature · 2006 · 5.2K citations
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
Hiroki Kato, Osamu Takeuchi, Shintaro Sato et al. · Nature · 2006 · 3.8K citations