HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection <i>ex vivo</i> and peculiar cytotoxic T lymphocyte activation phenotype

Asier Sáez‐Cirión, Christine Lacabaratz, Olivier Lambotte, +8

Proceedings of the National Academy of Sciences

Adaptive Immune SystemImmunologyImmunodominanceCd4 T Cell ResponsesT Cells +18

Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors

Étienne Patin, Milena Hasan, Jacob Bergstedt, +25

Nature Immunology

InflammationImmunogeneticsAllergyAutoimmune DiseaseNatural Variation +11

Functional Analysis via Standardized Whole-Blood Stimulation Systems Defines the Boundaries of a Healthy Immune Response to Complex Stimuli

Darragh Duffy, Vincent Rouilly, Valentina Libri, +46

Immunity

InflammationPsychoneuroimmunologyAllergyAutoimmune DiseaseMedicine +13

Heterogeneity in HIV Suppression by CD8 T Cells from HIV Controllers: Association with Gag-Specific CD8 T Cell Responses

Asier Sáez‐Cirión, Martine Sinet, So Youn Shin, +11

The Journal of Immunology

Distinctive roles of age, sex, and genetics in shaping transcriptional variation of human immune responses to microbial challenges

Barbara Piasecka, Darragh Duffy, Alejandra Urrutia, +52

Proceedings of the National Academy of Sciences

CD8+ T Cells Specific for EBV, Cytomegalovirus, and Influenza Virus Are Activated during Primary HIV Infection

Jean‐Marc Doisne, Alejandra Urrutia, Christine Lacabaratz, +5

The Journal of Immunology

Preserved Central Memory and Activated Effector Memory CD4⁺T-Cell Subsets in Human Immunodeficiency Virus Controllers: an ANRS EP36 Study

Simon J. Potter, Christine Lacabaratz, Olivier Lambotte, +11

Journal of Virology

Increased CD127 expression on activated FOXP3⁺CD4⁺ regulatory T cells

Federico Simonetta, Amel Chiali, Corinne Cordier, +5

European Journal of Immunology

Treg SubsetsT-regulatory CellImmunologyImmune RegulationRegulatory T Cells +17

Escape from highly effective public CD8+ T-cell clonotypes by HIV

María Candela Iglesias, Jorge R. Almeida, Solène Fastenackels, +19

Blood

Standardized Whole-Blood Transcriptional Profiling Enables the Deconvolution of Complex Induced Immune Responses

Alejandra Urrutia, Darragh Duffy, Vincent Rouilly, +45

Cell Reports