Concepedia

Leptin inhibits amyloid β-protein degradation through decrease of neprilysin expression in primary cultured astrocytes

Naoki Yamamoto, Mamoru Tanida, Yoko Ono, Rika Kasahara, Yuko Fujii, Kentaro Ohora, Kenji Suzuki, Kazuya Sobue

Biochemical and Biophysical Research Communications · 2014 · 25 citations · 16 references

DOI

Concepts

References

16

Insulin-degrading enzyme regulates the levels of insulin, amyloid β-protein, and the β-amyloid precursor protein intracellular domain <i>in vivo</i>

Wesley Farris, Stefan Mansourian, Yang Chang et al. · Proceedings of the National Academy of Sciences · 2003 · 1.5K citations · Full text

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Metabolic Regulation of Brain Aβ by Neprilysin

Nobuhisa Iwata, Satoshi Tsubuki, Yoshie Takaki et al. · Science · 2001 · 954 citations

, , +14

Identification of the major Aβ1–42-degrading catabolic pathway in brain parenchyma: Suppression leads to biochemical and pathological deposition

Nobuhisa Iwata, Satoshi Tsubuki, Yoshie Takaki et al. · Nature Medicine · 2000 · 862 citations

, , +13

Obesity‐related leptin regulates Alzheimer's Aβ

Darius C. Fewlass, Karina Noboa, F. Xavier Pi‐Sunyer et al. · The FASEB Journal · 2004 · 304 citations

, , +17

Leptin Increases Adult Hippocampal Neurogenesis in Vivo and in Vitro

Jacob C. Garza, Ming Guo, Wei Zhang et al. · Journal of Biological Chemistry · 2008 · 235 citations · Full text

, , +14