Tight control of gene expression in mammalian cells by tetracycline-responsive promoters.

Manfred Gossen, Heidelberg Bujard

Proceedings of the National Academy of Sciences

Viral ReplicationMolecular RegulationImmunologyMolecular BiologyEscherichia Coli +18

Mdm2 promotes the rapid degradation of p53

Ygal Haupt, Ruth Maya, Anat Kazaz, +1

Nature

Tumor BiologyMedicineRapid DegradationProtein DegradationTumor Suppressor +4

Regulation of p53 stability by Mdm2

Michael H.G. Kubbutat, Stephen N. Jones, Karen H. Vousden

Nature

Tumor BiologyTumor SuppressorMedicineCell BiologyCancer Research +1

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

Jamil Momand, Gerard P. Zambetti, David C. Olson, +2

Cell

Oncogenic AgentMedicineMolecular BiologyP53 ProteinP53-mediated Transactivation +7

Monoallelically Expressed Gene Related to p53 at 1p36, a Region Frequently Deleted in Neuroblastoma and Other Human Cancers

Mourad Kaghad, H Bonnet, Annie Yang, +10

Cell

Tumor BiologyGene RelatedTumor HeterogeneityMedicineRegion Frequently Deleted +8

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

Jonathan D. Oliner, Jennifer A. Pietenpol, Sam Thiagalingam, +3

Nature

Tumor BiologyOncogenic AgentMedicineCancer BiologyTumor Suppressor +6

p73 is a human p53-related protein that can induce apoptosis

Christine A. Jost, María C. Marín, William G. Kaelin

Nature

MitophagyApoptosisPathologyCell DeathHuman P53-related Protein +5

MDMX: a novel p53-binding protein with some functional properties of MDM2.

Wilma T. Steegenga, Nicole Riteco, Theo van Laar, +7

The EMBO Journal

Functional PropertiesMedicineMolecular BiologyNovel P53-binding ProteinTumor Suppressor +4

MDM2 Suppresses p73 Function without Promoting p73 Degradation

Xiaoya Zeng, Lihong Chen, Christine A. Jost, +7

Molecular and Cellular Biology

P73 DegradationApoptosisMolecular BiologyCell DeathChemical Biology +19

Inactivation of the p53-homologue p73 by the mdm2-oncoprotein

Matthias Dobbelstein, Sandra Wienzek, Claudia König, +1

Oncogene

Tumor BiologyP53-homologue P73Oncogenic AgentMedicineMolecular Biology +4