Cholesterol Crystals in Synovial Fluid

Abstract

Article1 March 1964Cholesterol Crystals in Synovial FluidJACK ZUCKNER, M.D., JAMAL UDDIN, M.D., GEORGE E. GANTNER JR., M.D., ROBERT W. DORNER, PH.D.JACK ZUCKNER, M.D.Search for more papers by this author, JAMAL UDDIN, M.D.Search for more papers by this author, GEORGE E. GANTNER JR., M.D.Search for more papers by this author, ROBERT W. DORNER, PH.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-60-3-436 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe finding of crystals in synovial fluid has been the subject of much current interest following the recent description by McCarty and Hollander (1) and others (2) of uric acid crystals in synovial fluid of patients with gout. The diagnostic significance of urate crystals in the synovial fluid of gouty patients has been stressed (1-3) and their probable relationship to the acute inflammatory reaction of gouty arthritis demonstrated (4, 5). McCarty, Kohn, and Faires (6) have also described crystals of calcium pyrophosphate in synovial fluid of patients with chondrocalcinosis or pseudogout. It has been shown that these latter crystals can...References1. MCCARTYHOLLANDER DJJL: The identification of urate crystals in gouty synovial fluid. Ann. Intern. Med. 54: 452, 1961. LinkGoogle Scholar2. ZVAILFLERPEKIN NJTJ: Significance of urate crystals in synovial fluid. Arch. Intern. Med. (Chicago) 111: 99, 1963. CrossrefMedlineGoogle Scholar3. HOLLANDER JL editor: Arthritis and Allied Conditions, 6th ed., Lea & Febiger, Philadelphia, 1960, p. 77. Google Scholar4. FAIRESMCCARTY JSDJ: Acute arthritis in man and dog produced by intrasynovial injection of sodium urate crystals. Clin. Res. 9: 329, 1961. Google Scholar5. 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Author, Article, and Disclosure InformationAffiliations: St. Louis, MissouriFrom the Section on Arthritis, Departments of Internal Medicine and Pathology, St. Louis University School of Medicine and the St. Louis University Hospitals, St. Louis, Missouri.This work was supported by grant T1 AM 5050 from the National Institute of Arthritis and Metabolic Diseases, United States Public Health Service, Bethesda, Maryland, and the Eastern Missouri Chapter, Arthritis and Rheumatism Foundation.Requests for reprints should be addressed to Jack Zuckner, M.D., Director, Section on Arthritis, Department of Internal Medicine, Saint Louis University School of Medicine, 1325 South Grand Boulevard, St. Louis 4, Missouri. 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