IDENTIFICATION OF URATE CRYSTALS IN GOUTY SYNOVIAL FLUID

Abstract

Article1 March 1961IDENTIFICATION OF URATE CRYSTALS IN GOUTY SYNOVIAL FLUIDDANIEL J. MCCARTY, M.D., JOSEPH L. HOLLANDER, M.D., F.A.C.P.DANIEL J. MCCARTY, M.D., JOSEPH L. HOLLANDER, M.D., F.A.C.P.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-54-3-452 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptUrate crystals have been noted in synovial fluid from gouty patients in the past, but this finding was believed to be infrequent and of little assistance to the clinician in his attempt to establish a diagnosis.1Recently one of us2reported that eight of 17 fluids from the affected joints of patients with clinical gout contained crystals seen by ordinary light microscopy, and in several of these cases the diagnosis of gout was first established on the basis of this finding.2It was noted that urate crystals in joint fluid were often short and rod-shaped, with rounded ends and parallel...Bibliography1. BauerCalkins WE, in Diseases of metabolism, edited by G. G. Duncan, p. 659. W. B. Saunders Co., Philadelphia, Pa., 1959. Google Scholar2. Hollander JL: Arthritis and allied conditions, 6th Ed., p. 77. Lea & Febiger, Philadelphia, Pa., 1960. Google Scholar3. Ro K: Biochem., Japan 14: 361, 1931. CrossrefGoogle Scholar4. RopesBauer MWW: Synovial fluid changes in joint disease, p. 92. Harvard University Press, Cambridge, Mass., 1953. Google Scholar5. Talbott JM: Gout, p. 40. Grune & Stratton, New York, 1957. Google Scholar6. Kling DM: The synovial membrane and the synovial fluid (with special reference to arthritis and injuries of the joints). Medical Press, Los Angeles, Calif., 1938. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Philadelphia, Pa.*Received for publication August 15, 1960.From the Arthritis Section, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pa.†Trainee, National Institute of Arthritis and Metabolic Diseases, USPHS.‡Chief, Arthritis Section, Department of Medicine, University of Pennsylvania School of Medicine.Requests for reprints should be addressed to Daniel J. McCarty, M.D., Department of Medicine, Hahnemann Medical College and Hospital, 230 N. Broad Street, Philadelphia 2, Pa. 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WEINBERGER, M.D., of in gout: crystals to hyperuricemia and acute arthritis in failure treated with Crystals in Synovial M.D., M.D., JR., M.D., W. and Hyperuricemia after for of Uric Acid and Its to of Gouty old and new of acute gouty joints, an ARTHRITIS IN AND OF URATE Significance of Calcium Crystals in the Synovial Fluid of The I. Clinical J. MCCARTY JR., M.D., N. M.D., Significance of Calcium Crystals in the Synovial Fluid of The II. Identification of N. M.D., J. MCCARTY JR., M.D., Treatment of Gout March acid March PDF