Paul A. Marks

Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

Michael S. Finnin, Jill R. Donigian, Alona Cohen et al. · Nature · 1999 · 1.7K citations

Life Sciences, Medicinal Chemistry, Molecular Biology +12

Histone deacetylase inhibitor selectively induces p21 ^WAF1 expression and gene-associated histone acetylation

Victoria M. Richon, Todd W. Sandhoff, Richard A. Rifkind et al. · Proceedings of the National Academy of Sciences · 2000 · 1.1K citations · Full text

Medicine, Molecular Biology, Oncology +16

A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases

Victoria M. Richon, Stéphane Emiliani, Eric Verdin et al. · Proceedings of the National Academy of Sciences · 1998 · 914 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +12

Phase I Study of an Oral Histone Deacetylase Inhibitor, Suberoylanilide Hydroxamic Acid, in Patients With Advanced Cancer

William Kevin Kelly, Owen A. O’Connor, Lee M. Krug et al. · Journal of Clinical Oncology · 2005 · 907 citations · Full text

Medicine, Oncology, Pharmacology +16

Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease

Emma Hockly, Victoria M. Richon, Benjamin Woodman et al. · Proceedings of the National Academy of Sciences · 2003 · 841 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17