Optimization of the TRAP assay to evaluate specificity of telomerase inhibitors

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

Nam W. Kim, Mieczyslaw A. Piatyszek, Karen R. Prowse et al. · Science · 1994 · 7.1K citations

Life Sciences, Cell Biology, Oncology +16

Telomerase activity in the regenerative basal layer of the epidermis inhuman skin and in immortal and carcinoma-derived skin keratinocytes.

C Härle-Bachor, Petra Boukamp · Proceedings of the National Academy of Sciences · 1996 · 500 citations

Life Sciences, Cell Biology, Molecular Biology +17

A highly selective telomerase inhibitor limiting human cancer cell proliferation

Klaus Damm · The EMBO Journal · 2001 · 421 citations · Full text

Medicine, Cell Biology, Oncology +12

Inhibition of human telomerase activity by peptide nucleic acids

James C. Norton, Mieczyslaw A. Piatyszek, Woodring E. Wright et al. · Nature Biotechnology · 1996 · 342 citations

Life Sciences, Biochemistry, Molecular Biology +12

A G-Quadruplex-Interactive Potent Small-Molecule Inhibitor of Telomerase Exhibiting in Vitro and in Vivo Antitumor Activity

Sharon Gowan, John Harrison, Lisa Patterson et al. · Molecular Pharmacology · 2002 · 289 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16