Concepedia
Gene Therapy · 2011 · 41 citations · 23 references
Open access
Knockout MouseGene TherapiesOtc DeficiencyAllergyMedicineImmunologyTherapeutic EfficacyGene VectorSpfash MiceSelf-complementary Aav2/8 VectorsCell Biology
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Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy.
Yang Yang, Frederick A. Nunes, Klára Berencsi et al. · Proceedings of the National Academy of Sciences · 1994 · 1.6K citations · Full text
Immunology, Recombinant Adenoviruses, Immunotherapy +19
Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy
Guangping Gao, Mauricio R. Alvira, Lili Wang et al. · Proceedings of the National Academy of Sciences · 2002 · 1.5K citations · Full text
Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer
Steven E. Raper, Narendra Chirmule, Frank S. Lee et al. · Molecular Genetics and Metabolism · 2003 · 1.5K citations
Inflammation, Autoimmune Disease, Disease Mechanism +9
MHC class I-cestricted cytotoxic T lymphocytes to viral antigens destroy hepatocytes in mice infected with E1-deleted recombinant adenoviruses
Yiping Yang, Hildegund C.J. Ertl, James M. Wilson · Immunity · 1994 · 607 citations
Medicine, Immunology, Antiviral Response +8
Self-complementary adeno-associated virus vectors containing a novel liver-specific human factor IX expression cassette enable highly efficient transduction of murine and nonhuman primate liver
Amit C. Nathwani, John T. Gray, Catherine Y. Ng et al. · Blood · 2005 · 417 citations · Full text