Concepedia

The ΔF508 mutation results in loss of CFTR function and mature protein in native human colon

Marcus Mall, Silvia M. Kreda, April Mengos, Timothy J. Jensen, Stephanie Hirtz, H. H. Seydewitz, James R. Yankaskas, Karl Kunzelmann, John R. Riordan, Richard C. Boucher

Gastroenterology · 2003 · 107 citations · 32 references

DOI

Concepts

References

32

Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis

Seng H. Cheng, Richard J. Gregory, John Marshall et al. · Cell · 1990 · 1.8K citations

, , +12

Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive

Gerene M. Denning, Matthew P. Anderson, Jane F. Amara et al. · Nature · 1992 · 1.2K citations

, , +9

Demonstration That CFTR Is a Chloride Channel by Alteration of Its Anion Selectivity

Matthew P. Anderson, Richard J. Gregory, Simon Thompson et al. · Science · 1991 · 1.1K citations

, , +17

Purification and functional reconstitution of the cystic fibrosis transmembrane conductance regulator (CFTR)

Christine E. Bear, Canhui Li, Norbert Kartner et al. · Cell · 1992 · 946 citations

, , +14

Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells

Devra P. Rich, Matthew P. Anderson, Richard J. Gregory et al. · Nature · 1990 · 706 citations

, , +14