Stephanie Hirtz

Lack of Neutrophil Elastase Reduces Inflammation, Mucus Hypersecretion, and Emphysema, but Not Mucus Obstruction, in Mice with Cystic Fibrosis–like Lung Disease

Stefanie Gehrig, Julia Duerr, Michael Weitnauer et al. · American Journal of Respiratory and Critical Care Medicine · 2014 · 156 citations · Full text

Veterinary Medicine, Immunology, Pathobiology +17

CFTR Cl− channel function in native human colon correlates with the genotype and phenotype in cystic fibrosis

Stephanie Hirtz, Tanja Gonska, H. H. Seydewitz et al. · Gastroenterology · 2004 · 145 citations · Full text

Life Sciences, Cell Biology, Physiology +13

Effects of Lumacaftor–Ivacaftor Therapy on Cystic Fibrosis Transmembrane Conductance Regulator Function in Phe508del Homozygous Patients with Cystic Fibrosis

Simon Y. Graeber, Christian Dopfer, Lutz Naehrlich et al. · American Journal of Respiratory and Critical Care Medicine · 2018 · 117 citations

Medicine, Pharmacology, Pharmacotherapy +15

Preventive but Not Late Amiloride Therapy Reduces Morbidity and Mortality of Lung Disease in βENaC-overexpressing Mice

Zhe Zhou, Diana Treis, Susanne Schubert‐Bast et al. · American Journal of Respiratory and Critical Care Medicine · 2008 · 111 citations

Medicine, Pharmacology, Pharmacotherapy +16

Hypoxic Epithelial Necrosis Triggers Neutrophilic Inflammation via IL-1 Receptor Signaling in Cystic Fibrosis Lung Disease

Benedikt Fritzsching, Zhe Zhou-Suckow, Joanna Trojanek et al. · American Journal of Respiratory and Critical Care Medicine · 2015 · 109 citations

Life Sciences, Immunology, Pathology +17