Longitudinal effects of elexacaftor/tezacaftor/ivacaftor on sputum viscoelastic properties, airway infection and inflammation in patients with cystic fibrosis

Laura Schaupp, Annalisa Addante, Mirjam Völler, +17

European Respiratory Journal

Lack of Neutrophil Elastase Reduces Inflammation, Mucus Hypersecretion, and Emphysema, but Not Mucus Obstruction, in Mice with Cystic Fibrosis–like Lung Disease

Stefanie Gehrig, Julia Duerr, Michael Weitnauer, +8

American Journal of Respiratory and Critical Care Medicine

Preventive but Not Late Amiloride Therapy Reduces Morbidity and Mortality of Lung Disease in βENaC-overexpressing Mice

Zhe Zhou, Diana Treis, Susanne Schubert‐Bast, +6

American Journal of Respiratory and Critical Care Medicine

Conditional deletion of Nedd4-2 in lung epithelial cells causes progressive pulmonary fibrosis in adult mice

Julia Duerr, Dominik Leitz, Magdalena Szczygieł, +20

Nature Communications

Airway Mucus Obstruction Triggers Macrophage Activation and Matrix Metalloproteinase 12–Dependent Emphysema

Joanna Trojanek, Amanda Cobos‐Correa, Stefanie Diemer, +12

American Journal of Respiratory Cell and Molecular Biology

InflammationInflammatory Lung DiseaseAllergyLung InflammationRespiratory Diseases +13

SLC26A9-mediated chloride secretion prevents mucus obstruction in airway inflammation

Pinelopi Anagnostopoulou, Brigitte Riederer, Julia Duerr, +14

Journal of Clinical Investigation

InflammationAsthmaCytokineInflammatory Lung DiseaseAllergy +11

Allergic airway inflammation induces a pro-secretory epithelial ion transport phenotype in mice

Pinelopi Anagnostopoulou, Lu Dai, Jolanthe Schatterny, +3

European Respiratory Journal

The K+ Channel Opener 1-EBIO Potentiates Residual Function of Mutant CFTR in Rectal Biopsies from Cystic Fibrosis Patients

Eva Roth, Stephanie Hirtz, Julia Duerr, +5

PLoS ONE

Personalized CFTR Modulator Therapy for G85E and N1303K Homozygous Patients with Cystic Fibrosis

Simon Y. Graeber, Anita Balázs, Niklas Ziegahn, +11

International Journal of Molecular Sciences

A novel thiol-saccharide mucolytic for the treatment of muco-obstructive lung diseases

Annalisa Addante, Wilfred W. Raymond, Irina Gitlin, +11

European Respiratory Journal