Christine E. Bear - Concepedia

Author

Christine E. Bear

Hospital for Sick Children ORCID

Also Known As

Bear C., Bear, Christine E., C Bear, C E Bear, C. Bear, C. E. Bear, C.E. Bear, CE Bear, CHRISTINE BEAR, Cameron Bear

250

Publications

10.3K

Citations

H-Index

132

Concepts

All Affiliations

Hospital for Sick Children University of Toronto SickKids Foundation University Health Network

About

Christine E. Bear is an author at Hospital for Sick Children specializing in medicine, cellular physiology, and cell biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	38	72	6.1K
2	Natural Sciences	25	31	2.7K
3	Health Sciences	8	8	332
4	Engineering	5	5	221
5	Allergy	3	3	89

Christine E. Bear

139

Publications

9.7K

Citations

H-Index

Page 1

	Year	Citations
Purification and functional reconstitution of the cystic fibrosis transmembrane conductance regulator (CFTR) Christine E. Bear, Canhui Li, Norbert Kartner, Cell Protein SecretionFibrosisSignal TransductionMolecular PhysiologyNatural Sciences	1992	943
Expression of the cystic fibrosis gene in non-epithelial invertebrate cells produces a regulated anion conductance Norbert Kartner, John W. Hanrahan, Tim Jensen, Cell Regulated Anion ConductanceCystic Fibrosis GeneFibrosisMolecular PhysiologySignal Transduction	1991	499
Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein Amy P. Wong, Christine E. Bear, Stephanie Chin, Nature Biotechnology Induced Pluripotent Stem CellDevelopmental BiologyDirected DifferentiationCell SpecializationMedicine	2012	424
Modulation of disease severity in cystic fibrosis transmembrane conductance regulator deficient mice by a secondary genetic factor Richard Rozmahe, Michael Wilschanski, Angabin Matin, Nature Genetics Knockout MouseDisease SusceptibilityMolecular PhysiologySignal TransductionDisease Mechanism	1996	387
The delta F508 mutation decreases the stability of cystic fibrosis transmembrane conductance regulator in the plasma membrane. Determination of functional half-lives on transfected cells. Gergely L. Lukács, X.B. Chang, Christine E. Bear, Journal of Biological Chemistry	1993	386
Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Potentiator VX-770 (Ivacaftor) Opens the Defective Channel Gate of Mutant CFTR in a Phosphorylation-dependent but ATP-independent Manner Paul D. W. Eckford, Canhui Li, Mohabir Ramjeesingh, Journal of Biological Chemistry	2012	304
Directed differentiation of cholangiocytes from human pluripotent stem cells Mina Ogawa, Shinichiro Ogawa, Christine E. Bear, Nature Biotechnology Induced Pluripotent Stem CellDevelopmental BiologyDirected DifferentiationMedicineStem Cell Research	2015	303
ATPase Activity of the Cystic Fibrosis Transmembrane Conductance Regulator Canhui Li, Mohabir Ramjeesingh, Wei Wang, Journal of Biological Chemistry	1996	267
Cl- channel activity in Xenopus oocytes expressing the cystic fibrosis gene. Christine E. Bear, F. Duguay, Angela Naismith, Journal of Biological Chemistry Cl- Channel ActivityMolecular BiologyCytoskeletonCellular PhysiologyHyperpolarization (Biology)	1991	192
The cystic fibrosis mutation (ΔF508) does not influence the chloride channel activity of CFTR Canhui Li, Mohabir Ramjeesingh, Evangelica Reyes, Nature Genetics FibrosisSignal TransductionMolecular PhysiologyPhysiologyMolecular Biology	1993	189

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