Christine E. Bear

Purification and functional reconstitution of the cystic fibrosis transmembrane conductance regulator (CFTR)

Christine E. Bear, Canhui Li, Norbert Kartner et al. · Cell · 1992 · 946 citations

Life Sciences, Cell Biology, Molecular Biology +14

Expression of the cystic fibrosis gene in non-epithelial invertebrate cells produces a regulated anion conductance

Norbert Kartner, John W. Hanrahan, Tim Jensen et al. · Cell · 1991 · 499 citations

Life Sciences, Genetics, Molecular Biology +14

Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein

Amy P. Wong, Christine E. Bear, Stephanie Chin et al. · Nature Biotechnology · 2012 · 433 citations · Full text

Life Sciences, Cell Biology, Molecular Medicine +16

The delta F508 mutation decreases the stability of cystic fibrosis transmembrane conductance regulator in the plasma membrane. Determination of functional half-lives on transfected cells.

Gergely L. Lukács, X.B. Chang, Christine E. Bear et al. · Journal of Biological Chemistry · 1993 · 388 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Modulation of disease severity in cystic fibrosis transmembrane conductance regulator deficient mice by a secondary genetic factor

Richard Rozmahe, Michael Wilschanski, Angabin Matin et al. · Nature Genetics · 1996 · 387 citations

Life Sciences, Genetics, Molecular Genetics +12