X.B. Chang

Conformational maturation of CFTR but not its mutant counterpart (delta F508) occurs in the endoplasmic reticulum and requires ATP.

Gergely L. Lukács, Asmaa Mohamed, Norbert Kartner et al. · The EMBO Journal · 1994 · 400 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +9

The delta F508 mutation decreases the stability of cystic fibrosis transmembrane conductance regulator in the plasma membrane. Determination of functional half-lives on transfected cells.

Gergely L. Lukács, X.B. Chang, Christine E. Bear et al. · Journal of Biological Chemistry · 1993 · 388 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Phosphatase inhibitors activate normal and defective CFTR chloride channels.

Frédéric Becq, Thomas Jensen, X.B. Chang et al. · Proceedings of the National Academy of Sciences · 1994 · 153 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Comparison of filler DNA at immune, nonimmune, and oncogenic rearrangements suggests multiple mechanisms of formation.

David B. Roth, X.B. Chang, John H. Wilson · Molecular and Cellular Biology · 1989 · 127 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

The cystic fibrosis transmembrane conductance regulator chloride channel. Iodide block and permeation

Joseph A. Tabcharani, X.B. Chang, J.R. Riordan et al. · Biophysical Journal · 1992 · 69 citations · Full text

Natural Sciences, Cell Biology, Molecular Biology +12