Spontaneous epileptiform discharges in a mouse model of Alzheimer's disease are suppressed by antiepileptic drugs that block sodium channels

Modification of seizure activity by electrical stimulation: II. Motor seizure

Ronald J. Racine · Electroencephalography and Clinical Neurophysiology · 1972 · 7.2K citations

Stimulation Device, Electrical Stimulation, Neurophysiology +14

Aberrant Excitatory Neuronal Activity and Compensatory Remodeling of Inhibitory Hippocampal Circuits in Mouse Models of Alzheimer's Disease

Jorge J. Palop, Jeannie Chin, Erik D. Roberson et al. · Neuron · 2007 · 1.6K citations · Full text

Compensatory Remodeling, Alzheimer's Disease, Brain Function +11

Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase

Joanna L. Jankowsky, Daniel J. Fadale, Jeffrey C. Anderson et al. · Human Molecular Genetics · 2003 · 1.6K citations · Full text

Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy

Frank H. Yu, Massimo Mantegazza, Ruth E. Westenbroek et al. · Nature Neuroscience · 2006 · 1.2K citations

Reduced Sodium, Neurophysiology, Cellular Neuroscience +11

Amyloid β-Induced Neuronal Hyperexcitability Triggers Progressive Epilepsy

Rimante Minkeviciene, Sylvain Rheims, Márton B. Dobszay et al. · Journal of Neuroscience · 2009 · 645 citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Neurophysiology +11