Aberrant Excitatory Neuronal Activity and Compensatory Remodeling of Inhibitory Hippocampal Circuits in Mouse Models of Alzheimer's Disease

Jorge J. Palop, Jeannie Chin, Erik D. Roberson, +10

Neuron

Compensatory RemodelingAlzheimer's DiseaseBrain FunctionMedicineDementia +9

Amyloid-β/Fyn–Induced Synaptic, Network, and Cognitive Impairments Depend on Tau Levels in Multiple Mouse Models of Alzheimer's Disease

Erik D. Roberson, Brian Halabisky, Jong W. Yoo, +10

Journal of Neuroscience

Synaptic TransmissionNeurochemical BiomarkersMultiple Mouse ModelsTau LevelsSynaptic Signaling +21

Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits

Jorge J. Palop, Brian W. Jones, Lisa Kekonius, +5

Proceedings of the National Academy of Sciences

Fyn Kinase Induces Synaptic and Cognitive Impairments in a Transgenic Mouse Model of Alzheimer's Disease

Jeannie Chin, Jorge J. Palop, Jukka Puoliväli, +5

Journal of Neuroscience

AMPA receptors regulate transcription of the plasticity-related immediate-early gene Arc

Vikram R. Rao, Sean A. Pintchovski, Jeannie Chin, +3

Nature Neuroscience

Transcriptional RegulationSynaptic PlasticitySignal TransductionDevelopmental BiologyMolecular Physiology +11

Reelin Depletion in the Entorhinal Cortex of Human Amyloid Precursor Protein Transgenic Mice and Humans with Alzheimer's Disease

Jeannie Chin, Catherine Massaro, Jorge J. Palop, +5

Journal of Neuroscience

Endogenous brain cytokine mRNA and inflammatory responses to lipopolysaccharide are elevated in the Tg2576 transgenic mouse model of Alzheimer’s disease

L M Sly, R F Krzesicki, John R. Brashler, +4

Brain Research Bulletin

InflammationInflammatory ResponsesNeurodegenerative DiseasesNeurobiology Of DiseaseAlzheimer's Disease +10

Fyn Kinase Modulates Synaptotoxicity, But Not Aberrant Sprouting, in Human Amyloid Precursor Protein Transgenic Mice

Jeannie Chin, Jorge J. Palop, Gui-Qiu Yu, +3

Journal of Neuroscience

Vulnerability of Dentate Granule Cells to Disruption of Arc Expression in Human Amyloid Precursor Protein Transgenic Mice

Jorge J. Palop, Jeannie Chin, Nga Bien‐Ly, +4

Journal of Neuroscience

Altered intrinsic neuronal excitability and reduced Na+ currents in a mouse model of Alzheimer's disease

Jon T. Brown, Jeannie Chin, Steven C. Leiser, +2

Neurobiology of Aging

Alzheimer's DiseaseNeurophysiologyComputational NeurosciencePhysiologyNeurotransmitter +8