Concepedia

HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells

Meera Natarajan, Jonathan Stewart, Erica A. Golemis, Elena N. Pugacheva, Konstantina Alexandropoulos, Braden D. Cox, W Wang, J. Robert Grammer, Candece L. Gladson

Oncogene · 2005 · 191 citations · 36 references

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36

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

Anne J. Ridley, Hugh F. Paterson, Caroline L. Johnston et al. · Cell · 1992 · 3.7K citations

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FAK integrates growth-factor and integrin signals to promote cell migration

David J. Sieg, Christof R. Hauck, Duško Ilić et al. · Nature Cell Biology · 2000 · 1.2K citations · Full text

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Tyrosine Phosphorylation of Focal Adhesion Kinase at Sites in the Catalytic Domain Regulates Kinase Activity: a Role for Src Family Kinases

Mihail CALALB, Thomas R. Polte, Steven K. Hanks · Molecular and Cellular Biology · 1995 · 987 citations · Full text

, , +17

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src.

Michael D. Schaller, Jeffrey D. Hildebrand, John D. Shannon et al. · Molecular and Cellular Biology · 1994 · 868 citations · Full text

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Increased expression of the epidermal growth factor receptor gene in malignant gliomas is invariably associated with gene amplification.

Albert J. Wong, Sandra H. Bigner, Darell D. Bigner et al. · Proceedings of the National Academy of Sciences · 1987 · 850 citations · Full text

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