Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

Ewan Birney, Shane Neph, Evelyn J. Cheung et al. · Nature · 2007 · 5.3K citations · Full text

Life Sciences, Bioinformatics, Genetics +14

In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector

Luigi Naldini, Ulrike Blömer, Philippe Gallay et al. · Science · 1996 · 4.9K citations

Pharmacy, Biotechnology, Molecular Medicine +14

<i>LMO2</i> -Associated Clonal T Cell Proliferation in Two Patients after Gene Therapy for SCID-X1

S. Hacein-Bey-Abina, Christof von Kalle, Manfred Schmidt et al. · Science · 2003 · 3.6K citations

Life Sciences, Genetics, Immunology +17

Repetitive zinc‐binding domains in the protein transcription factor IIIA from Xenopus oocytes.

Jim Miller, A. McLachlan, A. Klug · The EMBO Journal · 1985 · 2.5K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain.

Y G Kim, Srinivasan Chandrasegaran · Proceedings of the National Academy of Sciences · 1996 · 2.1K citations

Life Sciences, Biotechnology, Molecular Biology +15