Concepedia

The Carboxyl-Terminus of BACE Contains a Sorting Signal That Regulates BACE Trafficking but Not the Formation of Total Aβ

Lucia Pastorino, Annat Ikin, Angus C. Nairn, Amit Pursnani, Joseph D. Buxbaum

Molecular and Cellular Neuroscience · 2002 · 113 citations · 31 references

DOI

Concepts

References

31

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

Donald B. Smith, Kevin S. Johnson · Gene · 1988 · 6K citations

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β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE

Robert Vassar, Brian D. Bennett, Safura Babu‐Khan et al. · Science · 1999 · 3.8K citations · Full text

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Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity

Michael S. Wolfe, Weiming Xia, Beth L. Ostaszewski et al. · Nature · 1999 · 1.9K citations

, , +8

Membrane-anchored aspartyl protease with Alzheimer's disease β-secretase activity

Riqiang Yan, Michael J. Bienkowski, Mary E. Shuck et al. · Nature · 1999 · 1.4K citations

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Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

Ishrut Hussain, David J. Powell, David Howlett et al. · Molecular and Cellular Neuroscience · 1999 · 1.1K citations

, , +12