Concepedia

Pyruvate Kinase M2 Regulates Gene Transcription by Acting as a Protein Kinase

Xueliang Gao, Haizhen Wang, Jenny Yang, Xiaowei Liu, Zhi‐Ren Liu

Molecular Cell · 2012 · 767 citations · 32 references

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References

32

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

Heather R. Christofk, Matthew G. Vander Heiden, Marian H. Harris et al. · Nature · 2008 · 2.8K citations

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Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1

Weibo Luo, Hongxia Hu, Ryan Chang et al. · Cell · 2011 · 1.4K citations · Full text

, , +16

Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation

Weiwei Yang, Yan Xia, Haitao Ji et al. · Nature · 2011 · 1K citations · Full text

, , +7

Pyruvate kinase M2 is a phosphotyrosine-binding protein

Heather R. Christofk, Matthew G. Vander Heiden, Ning Wu et al. · Nature · 2008 · 1K citations

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Tyrosine Phosphorylation Inhibits PKM2 to Promote the Warburg Effect and Tumor Growth

Taro Hitosugi, Sumin Kang, Matthew G. Vander Heiden et al. · Science Signaling · 2009 · 781 citations · Full text

, , +17