The effect of glucosylceramide synthase on P-glycoprotein function in K562/AO2 leukemia drug-resistance cell line

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

R. L. Juliano, Victor Ling · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1976 · 3.3K citations

Medicine, Cell Biology, Pharmacology +11

Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine.

Kazumitsu Ueda, Carol Cardarelli, Michael M. Gottesman et al. · Proceedings of the National Academy of Sciences · 1987 · 1.1K citations · Full text

Medicine, Molecular Biology, Oncology +11

Clinical significance of P-glycoprotein in multidrug resistance malignancies [editorial] [see comments]

R.J. Arceci · Blood · 1993 · 226 citations · Full text

Medicine, Oncology, Pharmacology +14

Clinical significance of P-glycoprotein in multidrug resistance malignancies [editorial] [see comments]

R.J. Arceci · Blood · 1993 · 166 citations · Full text

Medicine, Oncology, Pharmacology +14

Glucosylceramide Synthase Blockade Down-Regulates P-Glycoprotein and Resensitizes Multidrug-Resistant Breast Cancer Cells to Anticancer Drugs

Valérie Gouazé‐Andersson, Yu Liu, Carlton S. Prickett et al. · Cancer Research · 2005 · 156 citations

Medicine, Oncology, Pharmacology +15