Concepedia

Methylation of CpG dinucleotides in the lacI gene of the Big Blue® transgenic mouse

Young Hyun You, Asanga Halangoda, Victoria L. Buettner, Kathleen A. Hill, Steve S. Sommer, Gerd P. Pfeifer

Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 1998 · 31 citations · 40 references

DOI

Concepts

References

40

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

Allan M. Maxam, Walter Gilbert · Methods in enzymology on CD-ROM/Methods in enzymology · 1980 · 14.7K citations

, , +13

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

Lawrence A. Donehower, Michele Harvey, Betty L. Slagle et al. · Nature · 1992 · 4.7K citations

, , +14

A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands.

Marianne Frommer, Louise E. McDonald, David Millar et al. · Proceedings of the National Academy of Sciences · 1992 · 3.3K citations

, , +14

5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

Adrian Merlo, James G. Herman, Li Mao et al. · Nature Medicine · 1995 · 2K citations

, , +17

Preferential Formation of Benzo[ <i>a</i> ]pyrene Adducts at Lung Cancer Mutational Hotspots in <i>P53</i>

Mikhail F. Denissenko, Annie Pao, Moon‐shong Tang et al. · Science · 1996 · 1.7K citations

, , +17