Pyrazole-induced cytochrome P-450 in rat liver microsomes: An isozyme with high affinity for dimethylnitrosamine

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

Ulrich K. Laemmli · Nature · 1970 · 251K citations

Protein Assembly, Natural Sciences, Structural Proteins +8

Separation and characterization of highly purified forms of liver microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls, phenobarbital, and 3-methylcholanthrene.

Dene E. Ryan, Daria Korzeniowski, Wayne Levin · Journal of Biological Chemistry · 1979 · 576 citations · Full text

Pharmacokinetics, Toxicological Mechanism, Oxidative Stress +19

Separation and purification of multiple forms of microsomal cytochrome P-450. Activities of different forms of cytochrome P-450 towards several compounds of environmental interest.

F. Peter Guengerich · Journal of Biological Chemistry · 1977 · 367 citations · Full text

Biochemistry, Medicine, Bioanalysis +7

Cobalt stimulation of heme degradation in the liver. Dissociation of microsomal oxidation of heme from cytochrome P-450

MD Maines, Attallah Kappas · Journal of Biological Chemistry · 1975 · 223 citations · Full text

Iron Metabolism, Cobalt Stimulation, Redox Biology +18

Microsomal metabolism of dimethylnitrosamine and the cytochrome P-450 dependency of its activation to a mutagen.

P. Czygan, Helmut Greim, Anthony J. Garro et al. · PubMed · 1973 · 211 citations

Molecular Biology, Summary Oxidative Demethylation, Microsomal Metabolism +19