Opinion paper: Stimulation of complement amplification or activation of the alternative pathway of complement?

Formation of the initial C3 convertase of the alternative complement pathway. Acquisition of C3b-like activities by spontaneous hydrolysis of the putative thioester in native C3.

Michael K. Pangburn, Robert D. Schreiber, Hans J. Müller‐Eberhard · The Journal of Experimental Medicine · 1981 · 443 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

The quantitative role of alternative pathway amplification in classical pathway induced terminal complement activation

M Harboe, G. Ulvund, Long Vien et al. · Clinical & Experimental Immunology · 2004 · 314 citations · Full text

Medicine, Immunology, Pathology +15

Naturally occurring anti-band-3 antibodies and complement together mediate phagocytosis of oxidatively stressed human erythrocytes.

H U Lutz, Federico Bussolino, R Flepp et al. · Proceedings of the National Academy of Sciences · 1987 · 216 citations · Full text

Life Sciences, Biochemistry, Immunology +11

The C3 convertase of the alternative pathway of human complement. Enzymic properties of the bimolecular proteinase

Michael K. Pangburn, Hans J. Müller‐Eberhard · Biochemical Journal · 1986 · 184 citations · Full text

Life Sciences, Biochemistry, Immunology +13

The binding of complement component C3 to antibody-antigen aggregates after activation of the alternative pathway in human serum

K J Gadd, K.B.M. Reid · Biochemical Journal · 1981 · 164 citations · Full text

Life Sciences, Biochemistry, Immunology +14