Fluorophosphonate derivatives of N9-benzylguanine as potent, slow-binding multisubstrate analogue inhibitors of purine nucleoside phosphorylase

Comprehensive medicinal chemistry

H. Timmerman, Aalt Bast, H. van der Goot et al. · Trends in Pharmacological Sciences · 1991 · 1.2K citations

Medicinal Chemistry, Active Ingredient, Natural Sciences +6

DIFFERENTIAL SPECTROPHOTOMETRY OF PURINE COMPOUNDS BY MEANS OF SPECIFIC ENZYMES

Herman Μ. Kalckar · Journal of Biological Chemistry · 1947 · 1.1K citations · Full text

Biochemistry, Gas Chromatography, Medicine +7

[17] The kinetics of reversible tight-binding inhibition

Jeffrey W. Williams, John F. Morrison · Methods in enzymology on CD-ROM/Methods in enzymology · 1979 · 687 citations

Biochemistry, Biochemical Interaction, Biomolecular Interaction +3

Structure-based design of inhibitors of purine nucleoside phosphorylase. 1. 9-(Arylmethyl) derivatives of 9-deazaguanine

John A. Montgomery, Shri Niwas, Jerry D. Rose et al. · Journal of Medicinal Chemistry · 1993 · 132 citations · Full text

9-(Difluorophosphonoalkyl)guanines as a new class of multisubstrate analog inhibitors of purine nucleoside phosphorylase

Serge Halazy, Anne Ehrhard, Charles Danzin · Journal of the American Chemical Society · 1991 · 131 citations

Pharmaceutical Science, Bioorganic Chemistry, Altmetric Attention Score +17