Computationally efficient flux variability analysis

Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox v2.0

Jan Schellenberger, Richard Que, Ronan M. T. Fleming et al. · Nature Protocols · 2011 · 1.9K citations · Full text

Metabolic Network, Systems Biology, Engineering +13

A genome‐scale metabolic reconstruction for <i>Escherichia coli</i> K‐12 MG1655 that accounts for 1260 ORFs and thermodynamic information

Adam M. Feist, Christopher S. Henry, Jennifer L. Reed et al. · Molecular Systems Biology · 2007 · 1.4K citations · Full text

Metabolic Network, Thermodynamic Information, Molecular Biology +6

Global reconstruction of the human metabolic network based on genomic and bibliomic data

Natalie C. Duarte, Scott A. Becker, Neema Jamshidi et al. · Proceedings of the National Academy of Sciences · 2007 · 1.4K citations · Full text

The effects of alternate optimal solutions in constraint-based genome-scale metabolic models

Radhakrishnan Mahadevan, Christophe H. Schilling · Metabolic Engineering · 2003 · 1.2K citations

Biology, Metabolic Network, Engineering +12

Quantitative prediction of cellular metabolism with constraint-based models: the COBRA Toolbox

Scott A. Becker, Adam M. Feist, Monica L. Mo et al. · Nature Protocols · 2007 · 796 citations

Metabolic Network, Engineering, Biochemistry +13