Concepedia

Activation of PPARα or γ Reduces Secretion of Matrix Metalloproteinase 9 but Not Interleukin 8 from Human Monocytic THP-1 Cells

Henry T. Shu, Birming Wong, Gaochao Zhou, Ying Li, Joel Berger, John Woods, Samuel D. Wright, Tian‐Quan Cai

Biochemical and Biophysical Research Communications · 2000 · 228 citations · 22 references

DOI

Concepts

References

22

Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor

Peter Tontonoz, Erding Hu, Bruce M. Spiegelman · Cell · 1994 · 3.5K citations

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The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation

Mercedes Ricote, Andrew C. Li, Timothy M. Willson et al. · Nature · 1998 · 3.5K citations

, , +10

PPAR-γ agonists inhibit production of monocyte inflammatory cytokines

Chengyu Jiang, Adrian T. Ting, Brian Seed · Nature · 1998 · 2.9K citations

, , +13

Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques.

Zorina S. Galis, Galina K. Sukhova, Michael W. Lark et al. · Journal of Clinical Investigation · 1994 · 2.5K citations · Full text

, , +16

mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer.

Peter Tontonoz, E Hu, Reed A. Graves et al. · Genes & Development · 1994 · 2.2K citations · Full text

, , +17