Concepedia

Proinflammatory Mediator Release

Proinflammatory Mediator Release is a biological process in which immune and resident cells within the periodontal tissues selectively secrete cytokines, chemokines, prostaglandins, and matrix metalloproteinases in response to microbial challenge, thereby initiating and amplifying the inflammatory cascade that contributes to connective tissue destruction and alveolar bone resorption in periodontitis.

1.3K

Publications

99.2K

Citations

7.9K

Authors

1.9K

Institutions

Publications per year

2017–2026

305

Parents

Publications

1.3K

Resveratrol Reduces the Proinflammatory Effects and Lipopolysaccharide- Induced Expression of HMGB1 and TLR4 in RAW264.7 Cells

Ying Yang, Shuping Li, Qiao Yang et al. · Cellular Physiology and Biochemistry · 2014 · 3.3K citations · Full text

, , +17

Current concepts in the diagnosis and management of cytokine release syndrome

Daniel W. Lee, Rebecca Gardner, David Porter et al. · Blood · 2014 · 2.8K citations

, , +14

RAGE Mediates a Novel Proinflammatory Axis

M. Hofmann, Steven Drury, Caifeng Fu et al. · Cell · 1999 · 1.9K citations · Full text

, , +17

Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-β1 secretion and the resolution of inflammation

Mai-Lan N. Huynh, Valerie A. Fadok, Peter M. Henson · Journal of Clinical Investigation · 2002 · 1.1K citations · Full text

, , +16

Purification of a human monocyte-derived neutrophil chemotactic factor that has peptide sequence similarity to other host defense cytokines.

Teizo Yoshimura, Koji Matsushima, Shuji Tanaka et al. · Proceedings of the National Academy of Sciences · 1987 · 990 citations · Full text

, , +16

1–5 of 1.3K

Authors

7.9K

  1. KJ
    Kevin J. Tracey

    Feinstein Institute for Medical Research, United States

    11 publications · 2.2K citations

    11

    h-index

  2. HW
    Haichao Wang

    Feinstein Institute for Medical Research, United States

    8 publications · 1.2K citations

    8

    h-index

  3. GM
    Gianni Marone

    University of Naples Federico II, Italy

    8 publications · 427 citations

    7

    h-index

  4. PW
    Ping Wang

    Feinstein Institute for Medical Research, United States

    6 publications · 429 citations

    6

    h-index

  5. HY
    Huan Yang

    Feinstein Institute for Medical Research, United States

    6 publications · 1.1K citations

    6

    h-index

1–5 of 7.9K

Institutions

1.9K

  1. Harvard University

    Cambridge, United States

    23 h-index

    93 publications

    10.9K citations

  2. Inserm

    Paris, France

    21 h-index

    127 publications

    9.7K citations

  3. Karolinska Institutet

    Stockholm, Sweden

    17 h-index

    59 publications

    5.5K citations

  4. Universidade de São Paulo

    São Paulo, Brazil

    14 h-index

    70 publications

    7.1K citations

  5. Feinstein Institute for Medical Research

    Manhasset, United States

    13 h-index

    70 publications

    8.4K citations

  6. University of Naples Federico II

    Naples, Italy

    13 h-index

    57 publications

    3K citations

  7. Karolinska University Hospital

    Stockholm, Sweden

    13 h-index

    44 publications

    3.9K citations

  8. University of Milan

    Milan, Italy

    12 h-index

    48 publications

    5.1K citations

1–8 of 1.9K

Venues

  1. The Journal of Immunology

    JI · 90 publications · 9.5K citations

    57

    h-index

  2. PubMed

    Repository · 40 publications · 2K citations

    27

    h-index

  3. Infection and Immunity

    IAI · 29 publications · 1.5K citations

    23

    h-index

  4. 21

    h-index

  5. Journal of Leukocyte Biology

    JLB · 21 publications · 1.3K citations

    19

    h-index

1–5