Design, synthesis, and structure–activity relationship studies of ATP analogues as DNA gyrase inhibitors

Structural Basis for Inhibition of the Hsp90 Molecular Chaperone by the Antitumor Antibiotics Radicicol and Geldanamycin

S. Mark Roe, Chrisostomos Prodromou, Ronan O’Brien et al. · Journal of Medicinal Chemistry · 1999 · 991 citations · Full text

Protein Assembly, Molecular Biology, Antimicrobial Chemotherapy +20

Crystal structure of an N-terminal fragment of the DNA gyrase B protein

Dale B. Wigley, G.J. Davies, E.J. Dodson et al. · Nature · 1991 · 520 citations

Crystal Structure, Biochemistry, Protein Assembly +6

Structure of CheA, a Signal-Transducing Histidine Kinase

A.M. Bilwes, Lisa A. Alex, Brian R. Crane et al. · Cell · 1999 · 479 citations · Full text

Signal Transduction, Signal-transducing Histidine Kinase, Biochemistry +6

Transformation of MutL by ATP Binding and Hydrolysis

Changill Ban, M.S. Junop, Wei Yang · Cell · 1999 · 402 citations · Full text

Cellular Enzymology, Biochemistry, Bioenergetics +5

The nature of inhibition of DNA gyrase by the coumarins and the cyclothialidines revealed by X-ray crystallography.

Richard J. Lewis, Okram Mukherjee Singh, Clare V. Smith et al. · The EMBO Journal · 1996 · 328 citations · Full text

X-ray Crystallography, Glycosylation, Biochemistry +5