Correlation Between Shiftide Activity and HIV-1 Integrase Inhibition by a Peptide Selected from a Combinatorial Library

Improved method for high efficiency transformation of intact yeast cells

Daniel Gietz, Andrew St. Jean, Robin A. Woods et al. · Nucleic Acids Research · 1992 · 3.3K citations · Full text

Engineering, Medicine, Biotechnology +7

Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated beta-galactosidase gene

J S Kimpton, Michael Emerman · Journal of Virology · 1992 · 915 citations · Full text

Viral Replication, Immunology, Viral Dynamic +20

The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells.

N K Heinzinger, M I Bukinsky, Sheryl Haggerty et al. · Proceedings of the National Academy of Sciences · 1994 · 842 citations

Viral Replication, Influences Nuclear Localization, Viral Polymerase Mechanism +18

Sensitivity of Human Immunodeficiency Virus Type 1 to the Fusion Inhibitor T-20 Is Modulated by Coreceptor Specificity Defined by the V3 Loop of gp120

Cynthia A. Derdeyn, Julie M. Decker, Jeffrey N. Sfakianos et al. · Journal of Virology · 2000 · 745 citations · Full text

Viral Replication, Immunology, Molecular Biology +17

Safety and efficacy of the HIV-1 integrase inhibitor raltegravir (MK-0518) in treatment-experienced patients with multidrug-resistant virus: a phase II randomised controlled trial

Beatriz Grinsztejn, Bach-Yen Nguyen, Christine Katlama et al. · The Lancet · 2007 · 566 citations · Full text

Multidrug-resistant Virus, Treatment And Prevention, Antiviral Drug Development +9